منابع مشابه
Investigation of Responsiveness to Thyrotropin-Releasing Hormone in Growth Hormone-Producing Pituitary Adenomas
Objective. The aim of this study was to investigate how the paradoxical response of GH secretion to TRH changes according to tumor volumes. Methods. Patients with newly diagnosed acromegaly were classified as either TRH responders or nonresponders according to the results of a TRH stimulation test (TST), and their clinical characteristics were compared according to responsiveness to TRH and tum...
متن کاملPituitary adenomas producing growth hormone in acromegalic patients.
Growth hormone was shown in histological sections of 25 pituitary adenomas from acromegalic patients by means of the unlabelled peroxidase-antiperoxidase (PAP) technique. On the basis of the numbers of cytoplasmic granules, the cells of the adenomas were of two types: densely granulated and sparsely granulated. The densely granulated cells had abundant cytoplasm containing numerous granules, wh...
متن کاملNEUROENDOCRINE CLINICAL CENTER BULLETIN Thyrotropin-secreting Pituitary Adenomas: Pitfalls in Diagnosis and Management
(SHBG): 73 nmol/l (normal, 13 to 71). His serum testosterone and the cortisol response on cosyntropin stimulation testing were normal. A presumptive diagnosis of a thyrotropin and growth hormone co-secreting pituitary adenoma was made. Octreotide LAR therapy was advised preoperatively to control thyroid hormone excess. He underwent transsphenoidal resection of the sellar mass, which was consist...
متن کاملPituitary adenomas and craniopharyngiomas.
Pituitary adenomas and craniopharyngiomas are similar in some aspects. Usually, they both are histologically benign, slow-growing intracranial tumors that arise in the sellar and parasellar areas, and tend to cause similar symptoms and signs, such as, but not limited to, progressive visual loss, progressive endocrine problems, and headache. They both are likely to have an excellent prognosis if...
متن کامل[Treatment of pituitary adenomas].
There has been a dramatic development in the treatment of pituitary adenomas during the last two decades. The main factors which led to this development were the introduction of transsphenoidal surgery, the development of new imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI) and the introduction of newer dopaminergic agents. Present status of the treatment...
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ژورنال
عنوان ژورنال: Journal of the Endocrine Society
سال: 2021
ISSN: 2472-1972
DOI: 10.1210/jendso/bvab048.1254